Heart Health

Heart Health

Cardiovascular diseases cause 1.9 million death per year in the EU – and cost almost 200 billion EUR per year in Europe.

Ubiquinol is required for at least 95 percent of your cellular energy production and is found in every cell in your body. The highest concentration is found in your heart, and promotes optimal cardiovascular health.

A recent 10-year study found Ubiquinol supports weak hearts and helped reduce patient’s symptoms[1]. Published in the prestigious Journal of the American College of Cardiology (2014), the study found supplementation with CoQ10 significantly reduced mortality in patients with a failing heart by 43 percent.

Caring for Your Heart with Ubiquinol

heartYour heart health is vital for life and you can take care of it with preventative measures as well as if you already have a heart condition.

Prevention is the best cure and cardiovascular health requires multiple approaches – in diet, lifestyle and medical care.

Everyone can work towards better heart health by following these steps:

 Eat for a Healthy Heart

  •  Healthy diet is essential for a healthy ticker
  • Eat a variety of foods including vegetables, wholegrains, fruit, nuts and seeds every day
  • Eat healthy fats from lean meat, poultry and oily fish
  • Limit sugary and salty take-away meals and snacks
  • Reduce intake of processed and packaged foods which contain additives
  • Drink mainly water
  • Supplement with Ubiquinol

While a healthy diet helps it is almost impossible to get enough Ubiquinol from food.

Be Active for Your Heart

Get moving. Regular, moderate-intensity physical activity is good for your heart and has been shown to help improve mood health.

Being active may also help with high blood pressure and being overweight.

The Australian Heart Foundation recommends that you include at least 30 minutes or more of moderate-intensity physical activity (such as brisk walking) on most, if not all, days of the week.

People with heart disease get the same benefits from regular moderate-intensity physical activity as others do. Studies show that Ubiquinol is essential for energy production and protects against oxidative stresses.

Control your Blood Pressure and Cholesterol

Cardiovascular diseases are due to multiple factors that culminate in inadequate blood supply to organs and failure of the heart to pump effectively among a host of other effects.

Blood Cholesterol

There are two types of blood cholesterol.

  • Low density lipoprotein (LDL) is also known as bad cholesterol because it can add to the build up of plaque in your arteries and increase your risk of getting coronary heart disease.
  • High density lipoprotein (HDL) is also known as good cholesterol because it helps to protect you against coronary heart disease.

Ubiquinol has been proven to help maintain healthy LDL cholesterol levels in healthy people.

Supplement with Ubiquinol

Numerous studies have shown that Ubiquinol (the active form of CoQ10) can help the heart and blood vessels in a number of ways.

Ubiquinol has been shown to increase the heart’s ejection fraction which is a measurement of the heart’s strength.

Cardiovascular Disease and Ubiquinol


Cardiovascular disease (disease of the heart or blood vessels) is one of the largest health problems and a major cause of death in Europe.

Research shows there are strong links between Ubiquinol consumption and good heart health.

Ubiquinol may even help to support people who already have CVD.

Reduced Adverse Heart Events (Study)

A significant long-term study, published in the Journal of the American College of Cardiology, found supplementation with CoQ10 significantly reduced adverse heart events like heart attacks by 43 percent.

The Q-Symbio study is one of the first long-term, international studies to show that CoQ10 improves symptoms and reduces major cardiovascular events.

The study found CoQ10 improved patients’ symptoms.

After two years of treatment, patients showed 43 percent fewer heart-related complications among the CoQ10-treated participants, including hospitalisation due to worsening of heart failure.

Increased Heart Strength (study)

In another study with patients with advanced congestive heart failure, Ubiquinol increased the strength of heart and its ability to pump blood by up to 17 percent.

Healthy people usually have ejection fraction rates of 55 to 70 percent, while patients in this study had less than 35 percent.

Researchers found Ubiquinol significantly boosted the heart ejection fraction ability in some cases by up to triple with significant improvement in quality of life. Also, other study showed that Ubiquinol had a positive impact on lowering LDL cholesterol and on the anti-inflammatory reaction[2].

Managing your Cholesterol with Ubiquinol


Cholesterol is a fatty compound found in the fats in your blood and is an important component of human health, but high levels of cholesterol in blood are linked to an increased risk of cardiovascular disease.

There are two types of blood cholesterol.

  • Low density lipoprotein (LDL) is also known as bad cholesterol because it can add to the build up of plaque in your arteries and increase your risk of getting coronary heart disease.
  • High density lipoprotein (HDL) is also known as good cholesterol because it helps to protect you against coronary heart disease.

To control your blood cholesterol levels you need to enjoy healthy eating. You might also need to take medicine to help to control your levels.

In addition, Ubiquinol has been proven to help maintain healthy LDL cholesterol levels in healthy people.

What is High Blood Cholesterol?

Total blood cholesterol levels above 5.5 mmol/L are an indication of a greatly increased risk of developing coronary heart disease. Levels above 6.5 mmol/L are considered to indicate extremely high risk.

Who has High Cholesterol?

Europeans suffer from the highest bad cholesterol in the world with a prevalence of 54% for both genders according to the WHO (World Health Organization).

Because high cholesterol itself does not have any symptoms, many people don’t know they have high cholesterol until their doctor requests a blood test.

Many factors can affect cholesterol including heredity, age and gender. But many are preventable as well as controllable. For example, diet, weight and exercise are factors that you can control and can also be used to prevent cholesterol from becoming an issue.

Statin Medications

Statins are often prescribed to lower cholesterol levels and help prevent cardiovascular disease.

But statin medications can also deplete your body of Ubiquinol, so if you’re taking or considering taking statins to help manage your cholesterol, talk to your doctor about supplementing with Ubiquinol.

Other Medications 

Niacin, fibrates, bile acid sequestrates and intestinal absorption blockers are alternatives to statin drugs that may help lower your cholesterol. Talk to your doctor first to see if any of these options are available to you.

Statin Drugs and Ubiquinol

Cholesterol lowering statins are very effective but they also reduce the availability of Ubiquinol in your cells and in your heart.

Statin drugs work by inhibiting your body’s internal production of cholesterol but they do not affect the cholesterol that you eat.

Unfortunately, they also deplete your natural Ubiquinol and other essential nutrients and vitamins.

How Ubiquinol Helps

Traditionally, Coenzyme Q10 has been one of the most popular heart health supplements used by people taking statin medications to lower their cholesterol.

Studies have shown Ubiquinol is the best way to restore healthy levels of total CoQ10 level if you are also taking statins.

Reduces Side Effects

The most common side effect of statins is myalgia (muscle pain). Studies have shown that deficiency of coenzyme Q10 may be related to deficiency of coenzyme Q10[2-4].

Research shows supplementing with Ubiquinol may help to reduce mild-to-moderate statin-related muscular pain[5].

Research has shown that Ubiquinol supplementation over a six month period can statistically, significantly reduce muscle pain and sensitivity by 53.8 percent. CoQ10 levels can also improve and in a particular study increased more than 194 percent[6].

Ubiquinol is the active and the most readily bio-available form of Coenzyme Q10. Thus, the potential for Ubiquinol to act as a direct response to help reduce statin related muscle pain is maximised.

References

  1. Harper CR, Jacobson TA: The broad spectrum of statin myopathy: from my­algia to rhabdomyolysis. Curr Opin Lipidol, 2007; 18: 401–8
  2. Wyman M, Leonard M, Morledge T: Coenzyme Q10: a therapy for hyper­tension and statin-induced myalgia? Cleve Clin J Med, 2010; 77: 435–42
  3. Marcoff L, Thompson PD: The role of coenzyme Q10 in statin-associated myopathy: a systematic review. J Am Coll Cardiol, 2007; 49: 2231–37
  4. Skarlovnik A, Janic M, Lunder M, Turk M, Sabovic M. Coenzyme Q10 Supplementation Decreases Statin-Related Mild-to-Moderate Muscle Symptoms: A Randomized Clinical Study. Med Sci Monit, 2014; 20:2183-2188.
  5. Lukas Zlatohlavek, Michal Vrablik, Barbora Grauova,Eva Motykova, Richard Ceska  The effect of coenzyme Q10 in statin myopathy, Neuroendocrinol Lett 2012; 33(Suppl.2):98–101;
  6. Cardiovascular disease kills one Australian every 12 minutes

[1] National Heart Foundation Chronic Heart Failure in Australia – http://www.heartfoundation.org.au/information-for-professionals/Clinical-Information/Pages/heart-failure.aspx

[2] Okamoto T. et al., (1989); Aberg F. et al., (1992); and Shindo Y. et al., (1994

[3] JACC Heart Fail. 2014 Sep 25. pii: S2213-1779(14)00336-9. doi: 10.1016/j.jchf.2014.06.008. http://www.ncbi.nlm.nih.gov/pubmed/25282031

[4] JACC Heart Fail. 2014 Sep 25. pii: S2213-1779(14)00336-9. doi: 10.1016/j.jchf.2014.06.008. http://www.ncbi.nlm.nih.gov/pubmed/25282031

[5] Bates A et al, Nursing and Health Sciences (2014)

Disclaimer

This website is accessible from many geographical locations, and the information that it provides regarding Ubiquinol™ is not applicable to nor intended to satisfy the requirements of all countries. Kaneka Pharma Europe supplies Ubiquinol™ as a raw material to companies that produce a variety of Ubiquinol™-containing products. Kaneka Pharma Europe does not make any claims regarding the use of these finished products and each manufacturer is responsible for ensuring that the claims made for and use of its products comply with the regulatory requirement of the locations in which it markets its products.