Ubiquinol, the active form of Coenzyme Q10, has been found to be significantly effective in improving the sperm quality of infertile men.

The study involved supplementation with Ubiquinol.

Ubiquinol is a powerful antioxidant and is present at high levels in sperm, protect sperm cells from oxidative damage and play a role in sperm cell energy production and motility working as a natural male enhancement.

The study, published in the Journal of Urology, involved 264 men with unexplained sperm problems including poor sperm numbers, low movement and abnormally shaped sperm. Each of these factors can decrease a man’s fertility.

More than a third of men aged over 40 years report having one or more reproductive health problems, all being more common among older men.

The men in the study had experienced infertility of more than one year and had abnormal sperm count and motility, according to World Health Organisation criteria.

The study involved supplementation with Ubiquinol – the active form of co-enzyme Q10.

The randomized, double-blind, placebo controlled trial was conducted over 26-week and showed Ubiquinol may help support healthy sperm.

The findings:

  • Ubiquinol significantly improved sperm count in more than 62 percent of men.
  • The number of mobile sperm also increased significantly in 57 percent.
  • The percentage of normally shaped sperm also improved in 52 percent of men who took Ubiquinol as compared to placebo.

Ubiquinol was more effective than conventional CoQ10 in improving sperm count and motility. Sperm density increased more than 2.5-fold with Ubiquinol compared to conventional CoQ10.

The study demonstrates that Ubiquinol supplementation significantly improves semen parameters in infertile men.


[1] Effects of the reduced form of coenzyme Q10 (Ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study.

[2] Centers for Disease Control and Prevention: Vital and Health Statistics, Series 23, No. 26.


This website is accessible from many geographical locations, and the information that it provides regarding Ubiquinol™ is not applicable to nor intended to satisfy the requirements of all countries. Kaneka Pharma Europe supplies Ubiquinol™ as a raw material to companies that produce a variety of Ubiquinol™-containing products. Kaneka Pharma Europe does not make any claims regarding the use of these finished products and each manufacturer is responsible for ensuring that the claims made for and use of its products comply with the regulatory requirement of the locations in which it markets its products.